Premarket Tobacco Product Applications (PMTA)

Helping you to show your product is appropriate for the protection of public health with Food and Drug Administration (FDA) approval.

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On 10 May 2016, the Food and Drug Administration (FDA) introduced legislation for the vaping industry in the United States – the Federal Food, Drug and Cosmetic Act.

What is PMTA?

PMTA is an abbreviation of Premarket Tobacco Product Application. It is a regulatory requirement for companies selling electronic cigarette and vaping products in the United States to comply with the new rules. 

The regulations aim to raise standards in the American vaping industry and protect consumers by ensuring all electronic cigarette and vaping products are safe to consume. The regulations pose massive challenges for businesses selling e-liquids and devices.

Does my product need a PMTA?

If you manufacture electronic cigarette or vaping products and want to sell them in the US market you will need a PMTA. This includes e-liquids and extends to companies who combine or modify affected products.

If you are unsure if your business is affected, contact Adact by calling (786) 706-4316 or emailing [email protected] for a quick answer.

What does PMTA include?

A PMTA is a detailed dossier of information which uses scientific data to demonstrate that a product is appropriate for the protection of public health which is sent to the Food and Drug Administration (FDA) who will reach a decision after considering:

  • the benefits and risks of the new tobacco product to the population as a whole, including people who would use the proposed product and non-users
  • whether people who currently use any tobacco product would be more or less likely to stop using such products if the new tobacco product were available
  • whether people who currently do not use any tobacco products would be more or less likely to begin using tobacco products if the new product were available
  • the methods, facilities, and controls used to manufacture, process, and pack the new tobacco product.

Proven experts

Adact has provided regulatory compliance services for thousands of companies across the world. We support your company by providing the advice and guidance to keep you ahead of the current regulations in the markets that matter.

Your champion

Adact delivers an excellent level of service which is still very affordable, making us a true champion for entrepreneurship. We believe in an approach that allows you and your company to grow a successful product range in the US marketplace.

Future-proof

Adact has proven that regulatory compliance is so much more than ticking boxes. It is about creating a platform that builds with you as future regulatory challenges occur for continued accountability and safety.

Good pedigree

Adact faces challenges and delivers industry beating results. From our ISO 17025 accredited testing laboratory we deliver world class regulatory compliance services which are further backed up with excellent on-demand custom service.

The contents of a PMTA from Adact

We have identified the potential for companies to come together and share the cost of producing base data that can support a large number of PMTAs. The FDA guidance references modelling and bridging data many times. On that basis, we see a great opportunity to generate data that meets the FDA’s requirements and reduces the overall cost.

We have identified the potential for companies to come together and share the cost of producing base data that can support a large number of PMTAs. The FDA guidance references modelling and bridging data many times. On that basis, we see a great opportunity to generate data that meets the FDA’s requirements and reduces the overall cost.

We have identified the potential for companies to come together and share the cost of producing base data that can support a large number of PMTAs. The FDA guidance references modelling and bridging data many times. On that basis, we see a great opportunity to generate data that meets the FDA’s requirements and reduces the overall cost.

We have identified the potential for companies to come together and share the cost of producing base data that can support a large number of PMTAs. The FDA guidance references modelling and bridging data many times. On that basis, we see a great opportunity to generate data that meets the FDA’s requirements and reduces the overall cost.

We have identified the potential for companies to come together and share the cost of producing base data that can support a large number of PMTAs. The FDA guidance references modelling and bridging data many times. On that basis, we see a great opportunity to generate data that meets the FDA’s requirements and reduces the overall cost.

We have identified the potential for companies to come together and share the cost of producing base data that can support a large number of PMTAs. The FDA guidance references modelling and bridging data many times. On that basis, we see a great opportunity to generate data that meets the FDA’s requirements and reduces the overall cost.

We have identified the potential for companies to come together and share the cost of producing base data that can support a large number of PMTAs. The FDA guidance references modelling and bridging data many times. On that basis, we see a great opportunity to generate data that meets the FDA’s requirements and reduces the overall cost.

We have identified the potential for companies to come together and share the cost of producing base data that can support a large number of PMTAs. The FDA guidance references modelling and bridging data many times. On that basis, we see a great opportunity to generate data that meets the FDA’s requirements and reduces the overall cost.

We have identified the potential for companies to come together and share the cost of producing base data that can support a large number of PMTAs. The FDA guidance references modelling and bridging data many times. On that basis, we see a great opportunity to generate data that meets the FDA’s requirements and reduces the overall cost.

We have identified the potential for companies to come together and share the cost of producing base data that can support a large number of PMTAs. The FDA guidance references modelling and bridging data many times. On that basis, we see a great opportunity to generate data that meets the FDA’s requirements and reduces the overall cost.

Postmarket reporting

The final step on the PMTA journey is postmarket reporting in which your company is required to maintain records and report on factors the FDA will use to determine whether there are any grounds to withdraw or temporarily suspend your marketing order. The two types of reporting are:

Adverse experience reporting

This covers the most serious adverse experiences such as; death, life-threatening events, inpatient hospitalisation, incapacitation of user, birth defect or any other adverse or serious condition affecting quality of life. These reports must be filed within fifteen days of identification.

Periodic reporting

These are less urgent reports which are filed annually and cover; changes to manufacturing, facilities, or controls that do not modify the finished product along with inventory of ongoing and completed studies, summary of sales and distribution data, current product purchasers, labelling changes and marketing and advertising plans. This also covers certain manufacturing deviations which could cause serious health consequences or death which are required to be reported within fifteen days of identification.